• Les résultats de l’essai ANRS VRI06 de phase I évaluant le candidat-vaccin CD40.HIVRI.Env publiés en octobre 2024 dans la revue eClinicalMedicine avait montré une bonne tolérance et l’apparition de réponses immunitaires cellulaires et humorales persistantes jusqu’à 48 semaines après la vaccination.
• En mai 2026, les résultats à long terme de l’essai ANRS VRI06 ont été publiés dans la revueScientific Reports: ils confirment la durabilité de la réponse immunitaire induite par ce candidat vaccin ciblant directement les cellules dendritiques.
• De plus ils montrent qu’un rappel administré plusieurs mois après la dernière vaccination (late boost) permet de réactiver fortement et durablement les réponses immunitaires dirigées contre le VIH.

There are many 88x31 buttons

The font must be something legilible with few pixels such as TomThumb.

The convert command of ImageMagick. A python script can center the text.

The entire Moby Dick can fit in a 88x39 button for the fun.
1) Generate the first GIF button file with
cat 22w.txt | convert -page 88x39+0+0 -background white -fill black -font tom.ttf -pointsize 6 text:- high.gif
2) Set 6 seconds per page: convert high.gif -set delay 600 -coalesce -repage 0x0 -crop 88x31+0+0 +repage good.gif

The GIF is 4.2MB and last 19 hours.

we were online is a browser extension—part game, artwork, and tool—that turns your Internet movement into a self-portrait of your time online. Cursor trails, keypresses and clicks, scroll patterns, and navigation rhythms, time on pages come to life on the pages you visit and show you how long you've spent on each page.

Christian was part of a team behind a landmark study that found that spending just 10 minutes relying on an AI tool significantly impairs our ability to focus and persist with difficult tasks

https://tinylittleoffice.com embed the whole document in the URL.

Il y a aussi un comparateur de la taille du lien selon les plateformes.

Freelance senior product and website designer with over 12 years of experience. I’ve worked for dozens of leading tech companies like Monzo, Pleo, Trustpilot, and Mastercard.

1. A browser extension has interfered with the site
2. A spotty connection hasn’t loaded the dependencies correctly
3. Internal IT policy has blocked dependencies
4. WIFI network has blocked certain CDNs
5. A user is viewing your site on a train which has just gone into a tunnel
6. A device doesn’t have enough memory available
7. There’s an error in your JavaScript
8. An async fetch request wasn’t fenced off in a try catch and has failed
9. A user has a JavaScript toggle accidentally turned off
10. A user uses a JavaScript toggle to prevent ads loading
11. An ad blocker has blocked your JavaScript from loading
12. A user is using Opera Mini
13. A user has data saving turned on
14. Rogue, interfering scripts have been added by Google Tag manager
15. The browser has locked up trying to parse your JS bundle

Pour justifier de classer la France comme pays à risque considérable, l’organisation indique que le pays « dispose d'un vaste dispositif institutionnel en matière de droits de l'homme, mais fait néanmoins preuve de défaillances persistantes et structurelles dans la prévention de la torture et des mauvais traitements. »

The tool is optimized for decompression.

LZ4 is symmetric: it compresses about as fast as it decompresses. That suits logs and swap, but not data that is shipped. A firmware image is compressed once on a build server and decompressed on every device that installs it, so time saved during compression helps nobody.

ZXC moves the work to the encoder. Match selection, optimal parsing and statistics tuning are done once, and the bitstream is laid out for the pipelines and branch predictors of modern processors. The decoder stays short, has few branches, and uses SIMD where it is available.

Additionally the "fix" fixes more than 40 separate issues in a single mega-commit touching 68 files which like. This is really beyond "you are trusting the slop machine too much". This is "the moment the slop machine got in your hands, a switch flipped in your head and you were like 'I never have to follow any engineering standards, any at all, ever again'". To repeat once again: "AI" is not a technology, it is a permission structure.

The good engineering practices are ignored by AI and the people seems to not care about it.

I find it completely overkill but maybe I am missing something. The use case for the posts is relevant, because it allows recursion (replies of replies). I don't see a potential widespread usage though.

The format is better than PNG and JPEG. As the browsers Edge, Firefox, and Safari supported the format respectively in 2018, in 2019 and in 2020. There is no reason to not use it.